Researchers analyzing protein-based drugs with mass spectrometry must handle challenges including analyte ion distribution over multiple charge states. The ZenoTOF 7600 system is a high-resolution mass spectrometry technology that pairs Zeno trap with electron activated dissociation (EAD) and allows scientists to accelerate drug discovery and development programs by identifying and localizing amino acid-specific post-translational modifications (PTMs) across all charge states. Additionally, scientists use this system to obtain highly descriptive fragment information and highly accurate positional confirmation; dramatically increase fragment ion coverage; and quickly and accurately produce intact and subunit results with confidence.
Explore this content pack by SCIEX to achieve
- Comprehensive analysis and characterization of next generation biologics, including monoclonal antibodies
- Enhanced product quality attribute investigation
- Advanced protein therapeutic characterization
- Comprehensive differentiation and localization of PTMs, including glycosylation, deamidation, and sulfation
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